ABSTRACT
Coronavirus disease 2019 (COVID-19) is the present global public health problem that has already caused pandemic since 2020. This respiratory corona viral infection can cause severe respiratory illness and death might be the outcome in severe cases. COVID-19 can manifest several atypical clinical presentations including neurological presentation. An important neurological problem is neurovascular thrombotic disorder A thrombotic event might be due to arterial or venous system affection. The study was conducted in the public laboratories on the outskirts of Baghdad after collecting 100 samples, (60) of people infected with Covid - 19 and (40) of healthy people and the ages of the people ranged from 18-80 years and the ages of the healthy ones from 18-70 years old. The study was conducted to investigate some biochemical indicators which includes Chemokine CXCL10, Fibrinogen, D-dimer, ferritin, C-reactive protein, iron and fibrinogen. The results showed a significant increase in the level of the chemokine CXCL10 in patients infected with Covid-19 virus compared to the control group, and a significant increase in the levels of D-dimer, ferritin, C-reactive protein, iron and fibrinogen which are important biochemical indicators in Covid - 19 patients. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.
ABSTRACT
Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. Respiratory symptoms ranging from mild to moderate appear on most of those infected with the virus and recover without the need for special therapeutic intervention. However, some of those who become infected develop severe symptoms and require medical attention. People who are most likely to develop severe symptoms of the disease are those with underlying diseases, such as cardiovascular disease.The study was conducted in the public laboratories on the outskirts of Baghdad after collecting 100 samples, (60) of people infected with Covid-19 and (40) of healthy people and the ages of the people ranged from 18-80 years and the ages of the healthy ones from 18-70 years old.The study was conducted to investigate some biochemical indicatorswhich includes creatine kinase, lactate dehydrogenase, glutathione and malonealdehyde, liver functions (AST, ALT and ALP).The results showed a significant increase in creatine kinase, lactate dehydrogenase, AST, ALT, ALP, and a significant increase in Malonaldehyde in all covid-19 patients and a decrease in glutathione in covid-19 patients.
ABSTRACT
This study included the preparation and identification of copper oxide nanoparticles (CuNPs) prepared from eucalyptus leaf extract using modern and advanced detection and analysis devices: XRD, AFM, SEM, UV-Vis, and TEM. The results of the tests indicated that the prepared particles are spherical and rod-shaped, with average diameters ranging from 32.55-37.94 nm, and the results showed that the copper oxide nanoparticles were within the nano-scale, and the wavelength of the drug is (322) nanometers. The factors affecting the loading of the drug (Favipiravir) at a concentration of (40 µg/mL) on the surface of activated charcoal prepared from eucalyptus leaves were studied, as well with a weight of 0.1 g and in the presence of copper oxide nanoparticles with different concentrations. It was found that the equilibrium time is 25 minutes, and the thermodynamic functions were calculated at different temperatures. The results illustrated that the loading process by using exothermic adsorption (physical adsorption), is less random process and spontaneously. The possibility of using the loaded substance (Favipiravir:CuNPs) to inhibit microorganisms such as viruses, bacteria, and fungi was studied, and by the presence of the surface active substance sodium dodecyl sulphate SDS, it was found that it has the ability to inhibit by 100%, as a result of the merging of the tail of the superficial active substances with the fatty membrane of the virus, the other microorganisms, its dismantling, and encapsulation of its parts. The vaccines and therapeutic drugs developed on the basis of nano-medicine, which are currently undergoing clinical trials, have the potential to become innovative alternatives to defeat COVID-19 in the future. Copyright © 2022 by SPC (Sami Publishing Company).